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The Food and Drug Administration, FDA, has approved the drug Vivitrol for the treatment of opioid dependence according to a news release by them on 10-12-2010.

Using two separate drugs to lose weight naturally can be very effective there are combinations before the FDA now awaiting approval. When dealing with weight-loss and the those who go through it you need to err along the side of caution and let the FDA do its job and demand some investigation be done so that the public recognizes the side effects and hazards of the medications before we drive them. Keep in mind that drug companies will be in business to make money and that they would say anything to keep people on their medications.

Researchers found out that participants investing in this drug to get a year, lost weight within 4 weeks and have kept the load off through the 56 weeks in the study. Contrave is really a combination from the drugs naltrexone and bupropion, which generally seems to reflect a brand new trend of weight-loss drugs which can be made up of more than one active ingredient, which may make them far better and safer.

Combo-pilling will be the newest fad or even better the newest to come under scrutiny and so it is just more publicly known recently, comb-pilling for weight loss has been around since the eighties. The biggest reason that employing a combination of pills is now popular may be the fact that as of right now there are no long term prescription diet pills that have been authorized by the FDA besides orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be licensed by the FDA.

Seizures are a side effect with Contrave and must not be taken in people who have seizure disorders. The drug can also raise hypertension and heart rate, and must not be used in people with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise blood pressure levels and heart rate and must not be used in patients with uncontrolled high hypertension, as well as by you are not heart-related and cerebrovascular (circulation dysfunction impacting your brain) disease. Patients with a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients to the increased chance of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stop smoking.


Acamprosate also works to eliminate the want to drink by reducing the the cravings for having a drink. The major difference between Naltrexone and Acamprosate is always that Acamprosate just isn't yet obtainable in the United States. While it has been widely studied in Europe the actual chemical reason why it works is still unknown. It is considered that it inhibits receptors within the brain which process glutamate, which in essence alters the way in which ones body reacts to alcohol intake. Several of the European research has revealed a lot of promise with Acamprosate in this some of the patients had a practically double effectiveness for staying sober.